EREDIVISIE 2020-2021 Ronde 22
| Pt | MP | W | D | L | F | A | GD | |||
| 1 | AFC Ajax | 54 | 22 | 17 | 3 | 2 | 69 | 16 | 53 | UCL |
| 2 | PSV Eindhoven | 47 | 22 | 14 | 5 | 3 | 51 | 24 | 27 | UCL |
| 3 | AZ Alkmaar | 43 | 22 | 12 | 7 | 3 | 48 | 32 | 16 | UEL |
| 4 | Feyenoord Rotterdam | 42 | 22 | 12 | 6 | 4 | 42 | 20 | 22 | PO |
| 5 | SBV Vitesse | 42 | 22 | 13 | 3 | 6 | 34 | 21 | 13 | PO |
| 6 | FC Groningen | 38 | 22 | 11 | 5 | 6 | 29 | 23 | 6 | PO |
| 7 | FC Twente | 33 | 22 | 9 | 6 | 7 | 35 | 28 | 7 | PO |
| 8 | SC Heerenveen | 32 | 22 | 8 | 8 | 6 | 31 | 29 | 2 | |
| - | FC Utrecht | 32 | 22 | 7 | 11 | 4 | 31 | 29 | 2 | |
| 10 | Fortuna Sittard | 28 | 22 | 8 | 4 | 10 | 33 | 41 | -8 | |
| 11 | Sparta Rotterdam | 26 | 22 | 7 | 5 | 10 | 31 | 34 | -3 | |
| 12 | Heracles Almelo | 25 | 22 | 7 | 4 | 11 | 23 | 33 | -10 | |
| 13 | PEC Zwolle | 23 | 22 | 4 | 11 | 7 | 26 | 34 | -8 | |
| 14 | VVV Venlo | 22 | 22 | 6 | 4 | 12 | 35 | 53 | -18 | |
| 15 | RKC Waalwijk | 19 | 22 | 4 | 7 | 11 | 19 | 35 | -16 | |
| 16 | Willem II | 14 | 22 | 3 | 5 | 14 | 25 | 47 | -22 | PO |
| 17 | ADO Den Haag | 14 | 22 | 2 | 8 | 12 | 20 | 48 | -28 | EE |
| 18 | FC Emmen | 6 | 22 | 0 | 6 | 16 | 17 | 51 | -34 | EE |
| Ronde 21 « || Ronde 22 || » Ronde 23 |
EREDIVISIE 2020-2021 Ronde 22
2021/02/12
| 20:00 | Mandemakers Stadion | ||
| RKC Waalwijk | 1-0 | FC Emmen |
| A.Touba 90' | 1-0 | |
2021/02/13
| 12:00 | Hitachi Capital Mobility Stadion | ||
| FC Groningen | 1-0 | PEC Zwolle |
| J.Larsen 16' | 1-0 | |
| 14:15 | Spartastadion Het Kasteel | ||
| Sparta Rotterdam | 1-2 | Fortuna Sittard |
| 0-1 | 23' Lisandro Semedo | |
| D.Gravenberch 31' | 1-1 | |
| 1-2 | 50' S.Polter | |
| 16:30 | Cars Jeans Stadion | ||
| ADO Den Haag | 2-2 | PSV Eindhoven |
| B.Adekanye 27' | 1-0 | |
| 1-1 | 51' D.Malen | |
| 1-2 | 76' D.Malen | |
| M.Kramer 90+3' | 2-2 | |
| 18:45 | Erve Asito | ||
| Heracles Almelo | 0-2 | AFC Ajax |
| 0-1 | 14' D.Klaassen | |
| 0-2 | 79' S.Haller | |
2021/02/14
| 12:15 | AFAS Stadion | ||
| AZ Alkmaar | 3-1 | SC Heerenveen |
| C.Stengs 20' | 1-0 | |
| T.Koopmeiners (pen) 47' | 2-0 | |
| 2-1 | 54' L.Schöne | |
| A.Guðmundsson 81' | 3-1 | |
| 14:30 | Stadion Galgenwaard | ||
| FC Utrecht | 3-1 | VVV Venlo |
| M.Mahi 61' | 1-0 | |
| B.Ramselaar 85' | 2-0 | |
| 2-1 | 90+1' G.Giakoumakis (pen) | |
| M.Mahi 90+5' | 3-1 | |
| 14:30 | De Kuip | ||
| Feyenoord Rotterdam | 5-0 | Willem II |
| J.Toornstra 45+2' | 1-0 | |
| B.Linssen 49' | 2-0 | |
| L.Sinisterra 52' | 3-0 | |
| S.Berghuis (pen) 63' | 4-0 | |
| O.Kökçü 83' | 5-0 | |
| 16:45 | GelreDome | ||
| SBV Vitesse | 0-2 | FC Twente |
| 0-1 | 16' Q.Menig | |
| 0-2 | 90+4' T.van Leeuwen | |