2.BUNDESLIGA 2020-2021 Spieltag 22
| Pt | MP | W | D | L | F | A | GD | |||
| 1 | Hamburger SV | 42 | 22 | 12 | 6 | 4 | 48 | 28 | 20 | I |
| 2 | Greuther Fürth | 42 | 22 | 12 | 6 | 4 | 43 | 25 | 18 | I |
| 3 | VfL Bochum | 42 | 22 | 13 | 3 | 6 | 40 | 23 | 17 | PO |
| 4 | KSV Holstein | 42 | 22 | 12 | 6 | 4 | 36 | 21 | 15 | |
| 5 | Karlsruher SC | 36 | 22 | 11 | 3 | 8 | 36 | 30 | 6 | |
| 6 | Fortuna Düsseldorf | 36 | 22 | 10 | 6 | 6 | 32 | 29 | 3 | |
| 7 | Hannover 96 | 33 | 22 | 10 | 3 | 9 | 33 | 25 | 8 | |
| 8 | 1. FC Heidenheim | 33 | 22 | 9 | 6 | 7 | 32 | 29 | 3 | |
| 9 | Erzgebirge Aue | 32 | 22 | 9 | 5 | 8 | 31 | 30 | 1 | |
| 10 | SC Paderborn 07 | 31 | 22 | 8 | 7 | 7 | 28 | 26 | 2 | |
| 11 | FC St. Pauli | 28 | 22 | 7 | 7 | 8 | 36 | 40 | -4 | |
| 12 | 1. FC Nürnberg | 26 | 22 | 7 | 5 | 10 | 29 | 34 | -5 | |
| 13 | Jahn Regensburg | 26 | 22 | 6 | 8 | 8 | 24 | 29 | -5 | |
| 14 | SV Darmstadt 98 | 25 | 22 | 7 | 4 | 11 | 34 | 39 | -5 | |
| 15 | VfL Osnabrück | 22 | 22 | 6 | 4 | 12 | 22 | 33 | -11 | |
| 16 | Eintracht Braunschweig | 20 | 22 | 5 | 5 | 12 | 21 | 43 | -22 | PO |
| 17 | SV Sandhausen | 18 | 22 | 5 | 3 | 14 | 25 | 44 | -19 | III |
| 18 | Würzburger Kickers | 15 | 22 | 4 | 3 | 15 | 25 | 46 | -21 | III |
| Spieltag 21 « || Spieltag 22 || » Spieltag 23 |
2.BUNDESLIGA 2020-2021 Spieltag 22
2021/02/19
| 18:30 | Sparkassen-Erzgebirgsstadion | ||
| Erzgebirge Aue | 1-0 | VfL Bochum |
| G.Bussmann 29' | 1-0 | |
| 18:30 | Eintracht-Stadion | ||
| Eintracht Braunschweig | 2-0 | Jahn Regensburg |
| J.Nikolaou 58' | 1-0 | |
| N.Proschwitz 65' | 2-0 | |
2021/02/20
| 13:00 | Benteler-Arena | ||
| SC Paderborn 07 | 2-1 | SV Sandhausen |
| 0-1 | 15' B.Halimi | |
| D.Srbeny 36' | 1-1 | |
| C.Antwi-Adjej 74' | 2-1 | |
| 13:00 | Stadion an der Bremer Brücke | ||
| VfL Osnabrück | 1-2 | 1. FC Heidenheim |
| 0-1 | 42' T.Kleindienst | |
| 0-2 | 50' O.Hüsing | |
| C.Santos 88' | 1-2 | |
| 13:00 | Millerntor-Stadion | ||
| FC St. Pauli | 3-2 | SV Darmstadt 98 |
| G.Burgstaller 26' | 1-0 | |
| O.Marmoush 62' | 2-0 | |
| 2-1 | 64' T.Skarke | |
| 2-2 | 66' S.Dursun | |
| G.Burgstaller 82' | 3-2 | |
2021/02/21
| 13:30 | Merkur Spiel-Arena | ||
| Fortuna Düsseldorf | 3-2 | Hannover 96 |
| R.Hennings (pen) 28' | 1-0 | |
| 1-1 | 37' F.Muslija | |
| F.Klaus 52' | 2-1 | |
| S.Appelkamp 76' | 3-1 | |
| 3-2 | 79' M.Gudra | |
| 13:30 | Wildparkstadion | ||
| Karlsruher SC | 0-1 | 1. FC Nürnberg |
| 0-1 | 90' M.Dæhli | |
| 13:30 | Flyeralarm Arena | ||
| Würzburger Kickers | 3-2 | Hamburger SV |
| M.Hasek 19' | 1-0 | |
| Douglas 30' | 2-0 | |
| P.Sontheimer 54' | 3-0 | |
| 3-1 | 72' J.Dudziak | |
| 3-2 | 89' B.Wood | |
2021/02/22
| 20:30 | Sportpark Ronhof Thomas Sommer | ||
| Greuther Fürth | 2-1 | KSV Holstein |
| 0-1 | 4' J.Mees | |
| H.Nielsen 27' | 1-1 | |
| OG (A.Mühling) 83' | 2-1 | |