MAJOR LEAGUE SOCCER 2021
| EASTERN CONFERENCE | Pt | MP | W | D | L | F | A | GD | ||
| 1 | New England Revolution | 11 | 6 | 3 | 2 | 1 | 7 | 6 | 1 | FS |
| 2 | Orlando City | 9 | 5 | 2 | 3 | 0 | 6 | 2 | 4 | PO |
| 3 | New York City | 8 | 5 | 2 | 2 | 1 | 10 | 4 | 6 | PO |
| 4 | Atlanta United | 8 | 5 | 2 | 2 | 1 | 6 | 4 | 2 | PO |
| 5 | CF Montréal | 8 | 6 | 2 | 2 | 2 | 8 | 7 | 1 | PO |
| 6 | Philadelphia Union | 8 | 6 | 2 | 2 | 2 | 5 | 5 | 0 | PO |
| 7 | Inter Miami | 8 | 6 | 2 | 2 | 2 | 8 | 9 | -1 | PO |
| 8 | Nashville SC | 7 | 5 | 1 | 4 | 0 | 6 | 4 | 2 | |
| 9 | New York Red Bulls | 6 | 5 | 2 | 0 | 3 | 7 | 6 | 1 | |
| 10 | D.C. United | 6 | 6 | 2 | 0 | 4 | 5 | 10 | -5 | |
| 11 | Columbus Crew | 5 | 5 | 1 | 2 | 2 | 3 | 4 | -1 | |
| 12 | Toronto FC | 5 | 5 | 1 | 2 | 2 | 7 | 9 | -2 | |
| 13 | Chicago Fire | 1 | 5 | 0 | 1 | 4 | 3 | 10 | -7 | |
| 14 | FC Cincinnati | 1 | 4 | 0 | 1 | 3 | 4 | 13 | -9 | |
| WESTERN CONFERENCE | Pt | MP | W | D | L | F | A | GD | ||
| 1 | Seattle Sounders | 16 | 6 | 5 | 1 | 0 | 13 | 2 | 11 | FS |
| 2 | Los Angeles Galaxy | 12 | 5 | 4 | 0 | 1 | 10 | 8 | 2 | PO |
| 3 | Sporting Kansas City | 10 | 6 | 3 | 1 | 2 | 9 | 7 | 2 | PO |
| 4 | Colorado Rapids | 10 | 5 | 3 | 1 | 1 | 8 | 6 | 2 | PO |
| 5 | San Jose Earthquakes | 9 | 6 | 3 | 0 | 3 | 10 | 8 | 2 | PO |
| 6 | Houston Dynamo | 8 | 6 | 2 | 2 | 2 | 7 | 8 | -1 | PO |
| 7 | Real Salt Lake | 7 | 4 | 2 | 1 | 1 | 6 | 4 | 2 | PO |
| 8 | Vancouver Whitecaps | 7 | 6 | 2 | 1 | 3 | 5 | 7 | -2 | |
| 9 | Portland Timbers | 6 | 5 | 2 | 0 | 3 | 6 | 8 | -2 | |
| 10 | Austin FC | 6 | 5 | 2 | 0 | 3 | 5 | 7 | -2 | |
| 11 | Minnesota United | 6 | 6 | 2 | 0 | 4 | 5 | 10 | -5 | |
| 12 | FC Dallas | 5 | 5 | 1 | 2 | 2 | 6 | 6 | 0 | |
| 13 | Los Angeles FC | 5 | 5 | 1 | 2 | 2 | 5 | 6 | -1 |
| 2021/05/11 « || 2021/05/15 || » 2021/05/22 |
MAJOR LEAGUE SOCCER 2021
2021/05/15
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13:00 | Yankee Stadium
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| New York City | 1-1 | Toronto FC | ||||||
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12:30 | Dignity Health Sports Park
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| Los Angeles Galaxy | 2-0 | Austin FC | ||||||
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19:00 | Mercedes-Benz Stadium
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| Atlanta United | 1-0 | CF Montréal | |||
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19:30 | Subaru Park
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| Philadelphia Union | 1-0 | New York Red Bulls | |||
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19:00 | Allianz Field
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| Minnesota United | 1-0 | FC Dallas | |||
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19:00 | Dick's Sporting Goods Park
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| Colorado Rapids | 3-1 | Houston Dynamo | ||||||||||||
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19:30 | Rio Tinto Stadium
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| Real Salt Lake | 0-0 | Nashville SC |
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19:00 | Earthquakes Stadium
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| San Jose Earthquakes | 0-2 | Portland Timbers | ||||||
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2021/05/16
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13:00 | Children's Mercy Park
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| Sporting Kansas City | 3-0 | Vancouver Whitecaps | |||||||||
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16:00 | West End Stadium
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| FC Cincinnati | 2-3 | Inter Miami | |||||||||||||||
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18:00 | Gillette Stadium
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| New England Revolution | 1-0 | Columbus Crew | |||
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20:00 | Audi Field
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| D.C. United | 0-1 | Orlando City | |||
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18:30 | Lumen Field
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| Seattle Sounders | 2-0 | Los Angeles FC | ||||||
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