MAJOR LEAGUE SOCCER 2021
| EASTERN CONFERENCE | Pt | MP | W | D | L | F | A | GD | ||
| 1 | New England Revolution | 7 | 3 | 2 | 1 | 0 | 5 | 3 | 2 | FS |
| 2 | New York City | 6 | 3 | 2 | 0 | 1 | 8 | 2 | 6 | PO |
| 3 | Orlando City | 5 | 3 | 1 | 2 | 0 | 4 | 1 | 3 | PO |
| 4 | CF Montréal | 5 | 3 | 1 | 2 | 0 | 6 | 4 | 2 | PO |
| 5 | Atlanta United | 4 | 3 | 1 | 1 | 1 | 4 | 3 | 1 | PO |
| 6 | Inter Miami | 4 | 3 | 1 | 1 | 1 | 4 | 4 | 0 | PO |
| 7 | New York Red Bulls | 3 | 3 | 1 | 0 | 2 | 5 | 5 | 0 | PO |
| 8 | D.C. United | 3 | 3 | 1 | 0 | 2 | 3 | 6 | -3 | |
| 9 | Nashville SC | 3 | 3 | 0 | 3 | 0 | 4 | 4 | 0 | |
| 10 | Columbus Crew | 2 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | |
| 11 | Toronto FC | 1 | 2 | 0 | 1 | 1 | 4 | 6 | -2 | |
| 12 | Philadelphia Union | 1 | 3 | 0 | 1 | 2 | 1 | 4 | -3 | |
| 13 | Chicago Fire | 1 | 3 | 0 | 1 | 2 | 3 | 7 | -4 | |
| 14 | FC Cincinnati | 1 | 3 | 0 | 1 | 2 | 2 | 10 | -8 | |
| WESTERN CONFERENCE | Pt | MP | W | D | L | F | A | GD | ||
| 1 | Seattle Sounders | 7 | 3 | 2 | 1 | 0 | 8 | 1 | 7 | FS |
| 2 | San Jose Earthquakes | 6 | 3 | 2 | 0 | 1 | 8 | 4 | 4 | PO |
| 3 | Real Salt Lake | 6 | 2 | 2 | 0 | 0 | 5 | 2 | 3 | PO |
| 4 | Austin FC | 6 | 3 | 2 | 0 | 1 | 4 | 3 | 1 | PO |
| 5 | Los Angeles Galaxy | 6 | 3 | 2 | 0 | 1 | 6 | 7 | -1 | PO |
| 6 | Los Angeles FC | 5 | 3 | 1 | 2 | 0 | 4 | 2 | 2 | PO |
| 7 | FC Dallas | 4 | 3 | 1 | 1 | 1 | 5 | 4 | 1 | PO |
| 8 | Colorado Rapids | 4 | 3 | 1 | 1 | 1 | 2 | 3 | -1 | |
| 9 | Houston Dynamo | 4 | 3 | 1 | 1 | 1 | 4 | 4 | 0 | |
| 10 | Vancouver Whitecaps | 4 | 3 | 1 | 1 | 1 | 3 | 3 | 0 | |
| 11 | Sporting Kansas City | 4 | 3 | 1 | 1 | 1 | 4 | 5 | -1 | |
| 12 | Portland Timbers | 3 | 3 | 1 | 0 | 2 | 3 | 6 | -3 | |
| 13 | Minnesota United | 0 | 3 | 0 | 0 | 3 | 1 | 7 | -6 |
| 2021/04/23 « || 2021/05/01 || » 2021/05/07 |
MAJOR LEAGUE SOCCER 2021
2021/05/01
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13:00 | Red Bull Arena
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| New York Red Bulls | 2-0 | Chicago Fire | ||||||
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12:00 | Rio Tinto Stadium
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| Real Salt Lake | 3-1 | Sporting Kansas City | ||||||||||||
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15:00 | Saputo Stadium
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| CF Montréal | 0-0 | Columbus Crew |
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14:30 | BBVA Stadium
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| Houston Dynamo | 1-1 | Los Angeles FC | ||||||
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19:00 | Gillette Stadium
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| New England Revolution | 2-1 | Atlanta United | |||||||||
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19:30 | Exploria Stadium
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| Orlando City | 3-0 | FC Cincinnati | |||||||||
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19:30 | Subaru Park
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| Philadelphia Union | 0-2 | New York City | ||||||
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19:00 | Toyota Stadium
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| FC Dallas | 4-1 | Portland Timbers | |||||||||||||||
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19:00 | Allianz Field
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| Minnesota United | 0-1 | Austin FC | |||
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20:00 | Earthquakes Stadium
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| San Jose Earthquakes | 4-1 | D.C. United | |||||||||||||||
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2021/05/02
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12:00 | Nissan Stadium
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| Nashville SC | 0-0 | Inter Miami |
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18:00 | Lumen Field
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| Seattle Sounders | 3-0 | Los Angeles Galaxy | |||||||||
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19:00 | BC Place
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| Vancouver Whitecaps | 0-1 | Colorado Rapids | |||
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